When you are busy and have so much important stuff to write about, it is so much easier to go after the ‘low hanging fruit’. Much less effort is needed and when it so easy, you don’t need to think too hard about it. Research on reflexology never fails to deliver on that count.
Reflexology is total bunk; it is made up pseudoscientific bullshit that has no basis what-so-ever. There is absolutely no known physiological mechanism linking areas on the foot to different organ systems and not one clinical trial that stacks up to scrutiny shows that it works. Every single clinical trial on it either shows it does not work or if it shows it works, it has fatal flaws in the methodology (and as such should never have been published, let alone carried out) or more often than not, was not even a clinical trial on reflexology, but a clinical trial on a damn good foot massage. Almost everyone is going to feel better after a damn good foot massage, so measures of anxiety etc are going to improve, especially if a chronic illness is present. Being more relaxed after a damn good foot massage is going to affect a number of psychosocial factors as well as some physiological parameters. BUT, that is not evidence for the junk that is reflexology, that is evidence for a damn good foot massage.
I previously blogged about how randomized trials on reflexology almost always end up with the exact same number in each group, which is really hard to do if you randomize properly. That is just symptomatic of the methodology issues that affect clinical trials that are allegedly done on reflexology.
What brought this on today was this study on “reflexology” and EEG testing of cortical oscillatory waves in the brain. The research measured a whole lot of parameters in the brain before and after a massage stimulation of the point on the foot (plantar hallux) that reflexologists claim is linked to the brain. They found changes.
BUT, there was no ‘control’ or ‘placebo’ massage stimulation of any other areas of the foot, nor a separate control group. So we have no way of knowing if the massage stimulation was just that or if it was due to stimulation of the specific area that they claimed is linked to the brain.
And even if they did that, they did not find what they claim they found. The analysis consisted of multiple comparisons which means they need to do a Bonferroni adjustment to an acceptable p-value. This means none of their results were actually statistically significant like they claimed, so they found nothing and certainly did not found what they claimed they found.
Another reflexology paper to consign to the trash heap.
Even more embarrassingly for the authors and the journal is this picture and what they labeled the dorsum of the foot:
oh dear. See why research like this is such a ‘low hanging fruit’: so easy to go after, so easy to debunk and so easy to write. Next.
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What does apple cider debunking, overpronation and cigarette smoking, Oscon supplements for Severs disease and vaccines causing autism have to do with each other?
^^^ that is the final slide in a video from my Critical Thinking Boot Camp. Anyone who blogs about science always get responses and comments with anecdotes about what was written with responses that it either does or does not apply to them. The science either ‘sucks’ or is the ‘greatest thing since sliced bread’ depending on the anecdote! It has now reached the point where I just delete that anecdotal comments on my posts as they contribute nothing of use to the topic under discussion. Steve Novella succinctly summed this up:
It is almost inevitable that whenever we post an article critical of the claims being made for a particular treatment, alternative philosophy, or alternative profession, someone in the comments will counter a careful examination of published scientific evidence with an anecdote. Their arguments boils down to, “It worked for me, so all of your scientific evidence and plausibility is irrelevant.”
Health Benefits of Apple Cider My first example comes from a blog post by Melinda Moyer following an article she wrote on the health benefit of apple cider. These three quotes sum up the issue:
After getting hate mail for debunking the health claims of apple cider vinegar, I’m explaining why I rely on science, not rumors.
Last month, I wrote my first Truth Serum column, “What Apple Cider Vinegar Can—and Can’t—Do for Your Health,” which explored what the science says about apple cider vinegar’s supposed health effects. I found that there isn’t much evidence ACV can cure colds, heal acne, help you lose weight, or alleviate heartburn—and that vinegar can sometimes be harmful.
Then came the angry emails and Facebook posts. Readers chided me for interviewing researchers and doctors rather than people who have actually been helped by apple cider vinegar. Others felt the evidence is irrelevant; vinegar works for them, so they’ll keep using it. A few implied that my writing was unbalanced and unfair.
I am sure you can see the issue …
“The Truth about Overpronation” I and many others have written about the nonsense surrounding “overpronation” and no point litigating them here … again. To me the evidence is clear. The two most recent systematic reviews/meta-analyses show that it is only a small risk factor, but still statistically significant. I and others are forever dealing with what can only be called ‘clowns’ in social media who cherry pick the studies that show its not a risk factor and ignore those that show it is and then resort to the whole gambit of logical fallacies when called out on it. When the evidence is conflicted like that, you need to defer to what the formal systematic reviews and meta-analyses say (however my next blog post will be on how to bias a systematic review and meta-analysis!).
I only raise this now as a number of times recently I have seen this YouTube video used as “evidence” that “overpronation” is not a problem. Firstly, You Tube videos are not evidence of anything! Secondly, whenever you see “The Truth About…” in the title, there is typically less truth in the actual content. Thirdly, yes that video does show Haille Gebrselassie massively “overpronating”. He was a very good elite runner and almost never got an injury. It is held up as evidence that “overpronation” is not a problem and following on from that, foot orthotics can’t possibly work (Dunning-Kruger in full flight). So who are you going to believe? The anecdote or the preponderance of scientific evidence? I have been in exchanges several times in recent months on this one. What those using the anecdote (But…but…it worked for me!) fail to comprehend is that “overpronation” is a risk factor. It increases your risk or chances of getting a problem. So, of course, there are always going to be an example of people who “overpronate” and don’t get problems. That is NOT evidence. The analogy is that I do not think anyone will disagree that smoking is a risk factor for lung cancer. Just because there are anecdotes of people who smoke their whole lives and do not get lung cancer is NOT evidence that smoking is not a risk factor for lung cancer.
Oscon Supplements for Severs Disease Another one that came up for was that I wrote elsewhere about Oscon supplements for Severs disease (calcaneal apophysitis). Oscon is a supplement with ingredients that are at their best, are very very mildly anti-inflammatory. It is marketed specifically for Severs and Osgood-Schlatters, totally supported by testimonials on the website. Not one bit of research has shown that they work and the physiological mechanism that they could work by (very very mild anti-inflammatory) is certainly not specific to Severs and Osgood-Schlatters and there is no way that it could be. ‘Inflammation’ probably occurs in Severs and Osgood-Schlatters, but is not really seen as an important underpinning mechanism and certainly anti-inflammatory drugs are not used, nor recommended for their management. If the supplement “works” for Severs, then it “worked” because of the placebo effect, due to the natural history or anyone of the other seven reasons why ineffective treatments sometimes work. Try telling that to someone who used Oscon in their child and they got better. This was the response I got to what I wrote:
Sadly your report also has nothing to do with talking to people with first hand experience. My daughter is as a gymnast for 10 years, 6 years of which we’re at international level competing for Great Britain. She developed Severs at around 9 years old and it was awful, like watching a little old woman walk about. She had every treatment she could, physio, stretching, anti-inflammatories etc etc, nothing helped for 2 years, she had to ‘manage’ the times with intense pain. Someone in the gym mentioned Oscon and I ordered it, after looking it up on line and discovering it’s general use in the USA and also checking with British Gymnastics it was ‘safe’ from a competition/enhancement perspective. Within 1 WEEK she was 75% better, after 2 weeks it was 85% pain free and I couldn’t believe it. The last 15% was a privately paid for shoe insert made from a mould to support her foot. I told 2 other people about it and. Both had the same reaction for their children. Sadly this appears to be a word-of-mouth cire But there are plenty of discussion online to support what I’m saying. This is your first hand experience you should of had before writing your report
Placebo, natural history, etc. There is a reason that you should never rely on anecdotes. BUT, try telling that to those who have no idea about science, critical thinking and logical fallacies. Can you see the pattern that I am developing in this post?
Vaccines and Autism Lastly, and clearly, vaccines do not cause autism spectrum disorder (ASD). The evidence is clear and strong. Despite that, the cranks still make stuff up, lie, spout conspiracy theories, refer to retracted, debunked, irrelevant and poorly done studies to support the claims and ignore the strength and the overwhelming number of the well-done studies that show it’s not the case. One of the criticisms of the “science” by the cranks is that they do not take into account the experiences of those parents who children first developed the ASD symptoms following the MMR vaccine….therefore the “science” is wrong (not quite the “But…but…it worked for me!” … but it is still the belief in the anecdote outweighs the science). How much weight should be given to those parents whose child developed autism following the MMR vaccine?
‘Fallacy Man” over at the Logic of Science blog did an awesome job of addressing this (strongly suggest you read it). Using mathematical probably and some modelling based on prevalence data, it looks like that on average 154 children a day in the USA will start showing the signs of ASD (or 1079 a week or 4623 a month). This means that 154 children will start showing the signs of ASD within 24 hrs of getting the MMR vaccine (or 1079 within a week; or 4623 within a month). Now try convincing that parents of those 154 or 1079 or 4623 that it was not the vaccine and would have happened by chance anyway is going to be an exercise in futility. From there, they then fall into the cesspool, conspiracy theories and made up stuff of the antivaccine movement, especially if they have predispositions to those characteristics. What they fail to see is that 154 children will first show the signs of ASD in the 24 hours before they get the MMR vaccine (or 1079 in the week before; or 4623 in the month before).
Surely it is obvious why the science has to outweigh the anecdote to get to the bottom of the problem. In this oversimplified example, the epidemiological research will look if there are statistically significantly more than the 154 children within 24 hrs (or within 1079 a week or within 4623 a month) who develop the symptoms of ASD following the MMR vaccine. That research has been done and there isn’t. What has happened though is the parents of the 154 (or 1079; or 4623) each year become a force to be reckoned with, even though they are misguided. Significant resources have to be diverted to countering the message coming from the cranks in that community. Resources that could be better spent finding the real cause and doing real things that actually do help.
Conclusion: Hopefully, you can see where the ‘journey’ of this post has taken me. On my other blog, my tagline is “As always: I go where the evidence takes me until convinced otherwise…”. There is a reason for that and what I wrote above is that reason.
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